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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
| O'Larkin, Caden | MR | Frederick Keys | 27 | 01/22/1983 | Charlotte | USA | Right | Right | 6' 3" | 222 lbs | - |
| O'Toole, Thomas | SP | Frederick Keys | 33 | 06/28/1977 | Easley | USA | Right | Right | 5' 9" | 192 lbs | - |
| Okeyo, Umer | MR | Frederick Keys | 30 | 01/22/1980 | Nairobi | KEN | Switch | Right | 6' 1" | 187 lbs | - |
| Oliver, Kyle | MR | Kinston Indians | 18 | 09/14/1991 | Chicago | USA | Left | Left | 6' 2" | 220 lbs | - |
| Olson, Alex | 1B | Potomac Nationals | 29 | 11/11/1980 | Hackensack | USA | Right | Right | 6' 0" | 193 lbs | - |
| Ordóńez, Francisco | RF | Wilmington Blue Rocks | 27 | 05/22/1983 | Alfred | USA | Right | Right | 6' 1" | 195 lbs | - |
| Orr, Christian | CL | Lynchburg Hillcats | 19 | 04/03/1991 | Albuquerque | USA | Right | Right | 6' 2" | 230 lbs | - |
| Ortega, Alfredo | SS | Lynchburg Hillcats | 32 | 04/25/1978 | Santiago | DOM | Right | Right | 6' 2" | 220 lbs | - |
| Ortíz, Félix | LF | Lynchburg Hillcats | 18 | 12/09/1991 | Bayamón | PUR | Right | Right | 6' 2" | 175 lbs | - |
